Multiple reaction monitoring (MRM)-profiling with biomarker identification by LC-QTOF to characterize coronary artery disease
نویسندگان
چکیده
منابع مشابه
Proteomics Multiple Reaction Monitoring ( MRM ) Principles and Application to Coronary Artery Disease Gabriela
Multiple reaction monitoring (MRM) is a mass spectrometry technique based on selection of a peptide ion and one or more characteristic fragment ions. The MRM method has previously been shown to be specific, accurate, and reproducible between laboratories. Through the use of retention time windows, MRM-based quantitation can also be multiplexed to analyze and quantitate hundreds of proteins per ...
متن کاملProteomics Multiple Reaction Monitoring ( MRM ) Principles and Application to Coronary Artery Disease
Multiple reaction monitoring (MRM) is a mass spectrometry technique based on selection of a peptide ion and one or more characteristic fragment ions. The MRM method has previously been shown to be specific, accurate, and reproducible between laboratories. Through the use of retention time windows, MRM-based quantitation can also be multiplexed to analyze and quantitate hundreds of proteins per ...
متن کاملEvaluation of Extracellular Circulating Human MicroRNA-197 as a Target Biomarker in Patients with Coronary Artery Disease
Background: Coronary Artery Disease (CAD) refers to the reduction or blockage of all or part of the coronary arteries due to the process of atherosclerosis or the presence of a clot. The aim of this study was to investigate the association of serum miR-197 as a diagnostic index in patients with coronary artery disease. Methods: In this study, 100 patients with CAD were selected. Extraction of...
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ژورنال
عنوان ژورنال: The Analyst
سال: 2018
ISSN: 0003-2654,1364-5528
DOI: 10.1039/c8an01017j